Williams will compete in the women’s singles event, according to an announcement from Wimbledon on Tuesday.
The post on social media showed her standing on a grass field wearing white sneakers.
Williams has not played since an injury forced her to retire in a first-round match at Wimbledon last year.
The 23-time main champion reached the Wimbledon final in 2019 losing to Simona Halep, who is now working with former Williams coach Patrick Muratoglu.
Williams will return to the court for the first time in Eastbourne next week for LTA’s Rothesay International, where she will meet world-ranked 4th-ranked Ons Jabeur Tunisia in the doubles event, in what will be her first appearance in the tournament in nearly a year, according to the competition.
23-time Grand Slam champion Serena Williams, widely regarded as the goat in women’s tennis, says she still aims to beat Margaret Court’s record of 24 times.
“I should have been in like 30 or 32 (a Grand Slam singles title),” Williams told CNN’s Christian Amanpour earlier this year.
“I should have had (the record), really, I had so many chances to get it. But I’m not going to give up.”
Williams was forced to miss the Australian Open in January on the advice of her medical team, and announced in December that it wasn’t “the place I physically needed to compete”.
Wimbledon is scheduled to take place from June 27 to July 10 at the All England Lawn Tennis and Croquet Club.
Jill Martin, Alicia Lloyd and Christian Amanpour contributed reporting.